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Frank Hildebrand Selected Research

Multiple Trauma (Multiple Injuries)

12/2022Club cell protein (CC)16 as potential lung injury marker in a porcine 72 h polytrauma model.
1/2021Alterations of Phagocytic Activity and Capacity in Granulocytes and Monocytes Depend on the Pathogen Strain in Porcine Polytrauma.
11/2020Fracture fixation strategy and specific muscle tissue availability of neutrophilic granulocytes following mono- and polytrauma: intramedullary nailing vs. external fixation of femoral fractures.
10/2020Altered cell surface receptor dynamics and circulatory occurrence of neutrophils in a small animal fracture model.
1/2020Cardiac Glucose and Fatty Acid Transport After Experimental Mono- and Polytrauma.
10/2019Effect of Long-Term Polytrauma on Ventilator-Induced Diaphragmatic Dysfunction in a Piglet Model.
6/2019Epidemiology of open tibia fractures in a population-based database: update on current risk factors and clinical implications.
10/2018Using IL-6 concentrations in the first 24 h following trauma to predict immunological complications and mortality in trauma patients: a meta-analysis.
1/2018Analysis of skeletal muscle microcirculation in a porcine polytrauma model with haemorrhagic shock.
1/2018Comparative Analysis of the Regulatory T Cells Dynamics in Peripheral Blood in Human and Porcine Polytrauma.
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Frank Hildebrand Research Topics

Disease

58Wounds and Injuries (Trauma)
12/2022 - 03/2004
35Multiple Trauma (Multiple Injuries)
12/2022 - 09/2002
26Sepsis (Septicemia)
02/2022 - 10/2003
19Hemorrhagic Shock
01/2022 - 01/2005
19Hemorrhage
04/2021 - 01/2005
16Inflammation (Inflammations)
12/2022 - 10/2003
13Multiple Organ Failure (MODS)
06/2020 - 11/2004
9Contusions
01/2021 - 04/2005
8Lung Injury
12/2022 - 06/2015
8Disease Progression
02/2022 - 03/2005
8Femoral Fractures (Femoral Fracture)
11/2020 - 09/2005
8Hypothermia
01/2016 - 03/2004
7Shock
01/2022 - 02/2008
7Lacerations
01/2021 - 04/2013
3Edema (Dropsy)
12/2022 - 09/2006
3Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
12/2022 - 03/2007
3Infections
10/2020 - 03/2005
3Pneumonia (Pneumonitis)
03/2019 - 05/2014
2Femoral Neck Fractures
08/2022 - 06/2022
2Heterotopic Ossification (Ectopic Ossification)
07/2022 - 10/2009
2Frailty
06/2022 - 04/2022
2Neoplasms (Cancer)
05/2022 - 05/2021
2Tibial Fractures (Fracture, Tibial)
01/2021 - 01/2020
2Kyphosis
02/2020 - 02/2020
2Acute Lung Injury
06/2019 - 06/2015
2Open Fractures (Compound Fracture)
06/2019 - 11/2016
2Traumatic Brain Injuries (Traumatic Brain Injury)
01/2019 - 10/2016
2Systemic Inflammatory Response Syndrome (Sepsis Syndrome)
10/2018 - 05/2011
2Heart Arrest (Cardiac Arrest)
10/2016 - 04/2013
2Thoracic Injuries (Chest Injury)
04/2013 - 02/2005
1Pain (Aches)
08/2022
1Hip Fractures (Intertrochanteric Fractures)
08/2022
1Fatigue
06/2022
1Ewing Sarcoma (Sarcoma, Ewing)
05/2022
1Osteosarcoma (Osteogenic Sarcoma)
05/2022
1Margins of Excision
05/2022
1Knee Osteoarthritis
05/2022
1Osteoarthritis
05/2022
1Carpal Tunnel Syndrome
04/2022

Drug/Important Bio-Agent (IBA)

20CytokinesIBA
02/2022 - 07/2003
19Interleukin-6 (Interleukin 6)IBA
11/2020 - 10/2003
12salicylhydroxamic acid (SHAM)IBA
12/2022 - 04/2005
8Interleukin-8 (Interleukin 8)IBA
12/2022 - 02/2007
7Interleukin-10 (Interleukin 10)IBA
12/2017 - 10/2003
7Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2017 - 10/2003
4Biomarkers (Surrogate Marker)IBA
12/2022 - 01/2015
4Dehydroepiandrosterone (DHEA)IBA
05/2014 - 10/2003
3Proteins (Proteins, Gene)FDA Link
12/2022 - 06/2019
3macrophage stimulatory lipopeptide 2IBA
02/2022 - 06/2010
3InterleukinsIBA
01/2019 - 06/2006
3Toll-Like Receptors (Toll-Like Receptor)IBA
01/2017 - 03/2007
3Peroxidase (Myeloperoxidase)IBA
05/2014 - 09/2006
2sulforaphaneIBA
01/2022 - 01/2022
2Oxygen (Dioxygen)IBA
05/2021 - 01/2018
2LipopeptidesIBA
04/2021 - 06/2010
2(4- (((2- (3- fluoro- 4- (trifluoromethyl)phenyl)- 4- methyl- 1,3- thiazol- 5- yl)methyl)sulfanyl)- 2- methylphenoxy)acetic acidIBA
01/2018 - 01/2018
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2018 - 01/2018
2Adenosine Triphosphate (ATP)IBA
11/2016 - 03/2004
2Antimicrobial PeptidesIBA
11/2016 - 01/2014
2C-Reactive ProteinIBA
01/2015 - 01/2013
2Fibrinogen (Factor I)FDA Link
04/2013 - 02/2008
2ChemokinesIBA
08/2011 - 03/2007
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
08/2011 - 09/2006
2SteroidsIBA
01/2010 - 02/2007
2Flutamide (Eulexin)FDA LinkGeneric
11/2006 - 10/2006
24,4',4''- (4- propyl- ((1)H)- pyrazole- 1,3,5- triyl) tris-phenolIBA
09/2006 - 06/2006
2Estrogen ReceptorsIBA
09/2006 - 06/2006
1Indicators and Reagents (Reagents)IBA
12/2022
1Pharmaceutical PreparationsIBA
08/2022
1Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
07/2022
1polyetherketoneketoneIBA
06/2022
1PolymersIBA
06/2022
1polyetheretherketoneIBA
06/2022
1TitaniumIBA
06/2022
1Adrenal Cortex Hormones (Corticosteroids)IBA
04/2022

Therapy/Procedure

20Resuscitation
01/2022 - 09/2005
14Therapeutics
08/2022 - 10/2003
13Punctures
04/2021 - 10/2003
12Length of Stay
01/2022 - 02/2007
12Ligation
04/2021 - 10/2003
11Fracture Fixation
01/2021 - 07/2004
10Critical Care (Surgical Intensive Care)
12/2022 - 02/2005
8Induced Hypothermia
10/2016 - 03/2004
6Intramedullary Fracture Fixation
11/2020 - 11/2005
6Artificial Respiration (Mechanical Ventilation)
06/2020 - 08/2013
6Laparotomy
02/2020 - 06/2006
5Operative Surgical Procedures
04/2021 - 10/2006
3Hip Replacement Arthroplasty (Total Hip Replacement)
08/2022 - 11/2019
3Arthroplasty
07/2022 - 05/2022
3Anesthesia
01/2020 - 04/2013
3Thoracotomy
05/2018 - 04/2005
2Hemiarthroplasty
08/2022 - 01/2015
2Prostheses and Implants (Prosthesis)
11/2019 - 01/2017
2Mechanical Ventilators (Ventilator)
10/2019 - 02/2007
2Orthopedic Procedures
01/2015 - 09/2002
1Drug Therapy (Chemotherapy)
05/2022
1Operative Time
05/2022
1Radiotherapy
05/2022
1Knee Replacement Arthroplasty (Total Knee Replacement)
05/2022
1Injections
04/2022